Wednesday, December 2, 2020

Edward Graves

 

    
   Edward Graves, PhD, is a medical physicist at Stanford University's medical school. He received both his Bachelor's in 1996 and his PhD in 2001 in bioengineering from UC Berkley. According to his CV, Dr. Graves has held various research positions at UCSF and in the department of radiology at Massachusetts General Hospital. He currently teaches courses in topics like radiation oncology and radiation physics at Stanford University School of Medicine. He also has an impressive list of publications including 78 peer reviewed journal articles and 5 book chapters. In addition to these publications, Dr. Graves is a member of various societies dedicated to medical physics such as the Academy of Molecular Imaging, American Society of Therapeutic Radiology and Oncology, and the American Association of Physicists in Medicine. 

    Research in the Graves lab focuses on imaging such as PET/CT scans of cancer patients' tumors, how to better image tumors to provide more targeted radiation therapy, and how to use imaging to study tumor hypoxia. His lab's website states, "We are a multi-disciplinary group with expertise and engineering, biology, chemistry, medicine, and computer science." Therefore, his lab is carrying out important work that uses integrative techniques to develop a more holistic view of their research topics to provide the most effective results. One of his lab's studies titled, "The role of granulocyte macrophage colony stimulating factor (GM-CSF) in radiation-induced tumor cell migration" was published in 2018. They observed that the cytokine GM-CSF was expressed by tumor cells and plays a role in cancer regrowth after radiation therapy. However, they found that adding a polyethylene glycol chain to the cytokine did not increase aggressiveness after radiation. The Graves lab attempts to better understand the ways in which imaging and radiation can be used to design better treatments for cancer patients through integration of various biological, physical, and chemical techniques. 


References:

Vilalta, M., Brune, J., Rafat, M., Soto, L., & Graves, E. E. (2018). The role of granulocyte macrophage 

    colony stimulating factor (GM-CSF) in radiation-induced tumor cell migration. Clinical & 

    Experimental Metastasis35(4), 247–254. https://doi.org/10.1007/s10585-018-9877-y

https://profiles.stanford.edu/edward-graves?tab=bio

http://www.med.stanford.edu/graveslab.html

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